Published on 15 Jun 2015 | over 3 years ago
This illustration video deals with Development of Kidney system, the development of metanephros.The facts have been presented in a way that makes clear ideas. In just 7 and a half min whole topic has been dealt with ample detail.
Very use full, beautiful and highly comprehensive illustration with a lot of high yield facts and figures.
The mesonephros acts as a structure similar to the kidney that, in humans, functions between the sixth and tenth weeks of embryological life. Despite the similarity in structure, function, and terminology, however, the mesonephric nephrons do not form any part of the mature kidney or nephrons.
In humans, the mesonephros consists of units which are similar in structure and function to nephrons of the adult kidney. Each of these consists of a glomerulus, a tuft of capillaries which arises from lateral branches of dorsal aorta and drains into the inferior cardinal vein; a Bowman's capsule, a funnel like structure which surrounds the glomerulus; and a mesonephric tubule, a tube which connects the Bowman's capsule to the mesonephric duct. A unit consisting of a single glomerulus and the Bowman's capsule surrounding it is called renal corpuscle, and a unit consisting of single renal corpuscle with its associated mesonephric tubule is called a "nephron" or "excretory mesonephric un
Formation of each mesonephric nephron begins when a bit of the intermediate mesoderm adjacent to the mesonephric duct differentiates to form a mesonephric vesicle.
This vesicle then elongates to form the mesonephric tubule, attaching to the mesonephric duct on one side. Meanwhile, an artery from the dorsal aorta begins extending towards the mesonephric tubule. When these two structures contact each other, they form the glomerulus and the Bowman's capsule surrounding it. The mesonephric tubule is also known as the Wolffian tubules (or Kobelt's tubules).
On the medial side of the mesonephric duct, from the sixth cervical to the third lumbar segments, a series of tubules, the Wolffian tubules, develops. They increase in number by outgrowths from the original tubules. The change from solid masses of cells to instead become hollowed in the center. One end grows toward and finally opens into the mesonephric duct, the other dilates and is invaginated by a tuft of capillary bloodvessels to form a glomerulus.
The mesonephros as a whole produces urine from the 6th through the 10th week of development. Despite the similarity in structure, function, and terminology, however, the mesonephric nephrons do not form any part of the mature kidney or nephrons. As the more caudal nephrons form, the more cranial nephrons are already degenerating. In females the mesonephros degenerates entirely, though vestigial structures such as Gartner's ducts, the epoophoron, and paroophoron are common. In males, a few of the more caudal tubules will survive and give rise to the efferent ductules of the testis, the epididymis, vas deferens, seminal vesicle, as well as vestigial structures such as the appendix testis, appendix epididymis, and paradidymis
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