Published on 29 Jul 2016 | about 1 year ago Mrsa Disease, Mrsa Transmission, Mrsa In Urine, Mrsa Fact Sheet, Treatment Of Mrsa, Mrsa Vaccine . Methicillin-resistant Staphylococcus aureus (MRSA) is a bacterium responsible for several difficult-to-treat infections in humans.

MRSA is any strain of Staphylococcus aureus that has developed, through horizontal gene transfer and natural selection, multi- resistance to beta-lactam antibiotics, which include the penicillins (methicillin, dicloxacillin, nafcillin, oxacillin, etc.) and the cephalosporins.

Strains unable to resist these antibiotics are classified as methicillin-susceptible Staphylococcus aureus, or MSSA. The evolution of such resistance does not cause the organism to be more intrinsically virulent than strains of S. aureus that have no antibiotic resistance, but resistance does make MRSA infection more difficult to treat with standard types of antibiotics and thus more dangerous.

MRSA is especially troublesome in hospitals, prisons, and nursing homes, where patients with open wounds, invasive devices, and weakened immune systems are at greater risk of nosocomial infection (hospital-acquired infection) than the general public. MRSA began as a hospital-acquired infection, but has developed limited endemic status and is now sometimes community-acquired as well as livestock-acquired.

The terms HA-MRSA (healthcare-associated MRSA), CA-MRSA (community-associated MRSA) and LA-MRSA (livestock-associated) reflect this distinction.

Symptoms of MRSA

MRSA signs and symptoms depend on what area of the body is infected. Although many people carry MRSA bacteria in their mucosa (inside the nose), they may never display any symptoms of active infection.

Staph skin infections, including MRSA, appear as a bump or sore area of the skin that could be mistaken for an insect bite. The infected area might be:

Hot to the touch
Full of pus or other liquid
Accompanied by a fever.

Signs and symptoms of a serious MRSA infection in the blood or deep tissues include:

Fever of 100.4 degrees F or higher
Aches and pains of the muscles
Swelling and tenderness in the affected body part
Chest pains
Wounds that do not heal.

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